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Ehrlichia and your Dog

30/3/2022

 

What is Ehrlichia? 

Ehrlichia is a type of bacteria that infects the white blood cells of dogs. Ehrlichia is spread between dogs by the brown dog tick. There are several different types of Ehrlichia (named after the person who discovered it - Mr Ehrlich). The type we have in Australia is Ehrlichia canis.. 

Ehrlichia canis
infections can be very severe and make some dogs very sick or even kill them. Ehrlichia canis particularly infects the cell called platelets that are involved in clotting. Additionally the disease causes an inflammatory storm around the body. Because they hide inside the blood cell, it can make it very hard to kill the bacteria. 
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Should I be concerned for my dog? What are the Symptoms?

Ehrlicihia is a very serious illness affecting the clotting factors, immune system and the kidneys of the dog. Without treatment, many dogs will die from this disease.
There are three stages to this disease and there is some cross-over between the three stages.

Early symptoms can include:
  • Inappetence (some dogs are off food for only a few days)
  • Weight loss (despite being fed normal to increased amounts)
  • Fever (in some cases)
  • Lethargy
  • Sore eyes
  • Cloudy eyes
  • Abdominal discomfort
  • Vomiting and/or Diarrhoea
  • Slight Cough
  • Sore Joints
  • Nothing at all

Subclinical / Carrier Phase
  • ​Your dog appears fine but has some changes in its blood that remains undetectable unless a complete blood count is run. These blood changes can make surgery risky.

End Stage (a few months to many years into the disease)
  • Kidney Failure
  • Shut Down of the Immune System
  • Death

The early and subclinical stage is generally easily treated, but the end stage disease can be very hard to treat.
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How can I tell if my dog has Ehrlichia?

A simple blood test is all that is required to see if your dog has Ehrlichia. A complete blood count is performed and if there is indication of low clotting factors known as platelets, then there is a strong chance that your dog has Ehrlichia and treatment should be started. The blood sample will then be sent for confirmation at special labs. 
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Can Ehrlichia canis be Treated?

Yes. Ehrlichia can be treated in the early and subclinical stages with the antibiotic doxycycline. End stage disease can be very difficult or near impossible to treat. There however have been some new experimental treatments for the end stage disease and hopefully in the future we will have better options.

It is important that a full course of medication is given as if some bacteria is left behind, then the infection can recur

Can my dog catch it again?

Unfortunately yes. There has been cases where dogs have been re-infected. So prevention is really important

Can people catch this disease?

It is very unlikely for people to catch this disease. There have been no human cases in Australia or South East Asia of this strain. 

Is there a vaccine for Ehrlichia?

There are no vaccines for Ehrlichia. 

How do I prevent this disease?

Ehrlichia is quickly transmitted by ticks. It only takes as little as 3 hours of tick feeding for Ehrlichia to be transmitted from the tick to the dog. Additionally, recent evidence shows that Ehrlichia can be passed from the adult ticks to baby ticks, so once it is in an area, the ticks will continue to transmit this disease. Hence prevention is key to stopping this disease.

Primary preventative - It is important to use a product that repels ticks. Two products have shown to be extremely effective in preventing tick bites and Ehrlichia are SERESTO COLLARS and ADVANTIX SPOT ON. They are over 90% effective in preventing Ehrlichia
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Secondary preventative - It is recommended that a back up treatment is used that kills the ticks. Products such as Bravecto and Nexgard are excellent products that kill the tick but take 5 to 24 hours to kill them. So these are not great as a primary product, as they are only about 70% effective.  But when combined with a primary product, it reduces the risk of your dog contracting Ehrlichia even further. 

How did it get here?

This disease came from overseas. In mid 2020, Ehrlichia was discovered in Kununurra, WA for the first time. Within a week of its discovery, through the work of our vets, it was found to be in Katherine and Central Australia. And within months, a true picture emerged showing it expanding throughout northern WA and the NT. We were able to look back at cases and believe it may have been around in 2018, but likely not prior to that. We now know we have the South East Asian strain of this disease and somehow it was introduced into Australia. The strain we have is particularly severe, but so far we have seen in the early stages that it can be treated. 

Our clinics in Katherine and Alice Springs continue to investigate treatment options for this horrible disease.

 Canine Female Contraceptives in Remote Communities

20/1/2015

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There are many different forms of contraception for our canine companions that are effective in population control for remote community animals. Some are more effective than others, some have dangers attached and some contraceptives are prohibitively expensive. In this article, we will explore some of the main drugs that are used in remote community work.

So what are they and what do they actually do?

There are 2 main types of contraceptives that are used in remote community work, one family is called progestagens, and the other main family is GNRH antagonists.
- The progestagens (MPA® or Covinan®) mimic female hormones that make the dog think it is pregnant  By doing this, it stops the body’s production of eggs and hence acts as a contraceptive.
- GNRH antagonists (Suprelorin®) work in a different way by stopping the flow of oestrogen which will stop the dog becoming fertile.
Both of these types of drugs can be used successfully to reduce breeding of dogs in remote communities, but there can be side effects, so caution must be used.
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Administering the Contraceptive

What should we be looking for when trying to work out the best contraceptives for our community's dogs?

Well, we have to work out how frequently we have to use them. With the progestagen Covinan®, this drug needs to be used every 3 months. With the progestagen MPA, studies have shown that this is 98% effective if used every 5 months, and reduces to 90% if used every 6 months. With the GnRH antagonist, Suprelorin®, it is highly effective if used every 12 months, but it should be noted that a bitch will actually become more fertile for the first month.

So why don't we jump straight for the GnRH antagonist (Suprelorin®)?

The problem is that it is exceedingly expensive. The price of Suprelorin® is between 10 to 30 times more expensive than progestagens. In fact it is almost more expensive or equates to the cost of desexing a dog in some programs.
This means that for every Suprelorin® injection, 15 dogs could have had their 2 contraceptives each year.
The second problem is there is a very high risk of side effects. Some studies indicate that they can be as high as 60%.
So, it is our belief that it is better to use a progestagen for population control.

So when should we use them?

Female canine contraception can be incorporated into any effective dog program to help control dog numbers. It is important when organising a service provider that you direct them to the combination of drugs that you want for the animals in your community. In making this decision, it is vital to work out the timing of the visits in relation to the drugs being used. Please note, it is important to always incorporate desexing into any dog program as this will give permanent contraception. Contraceptives should only be used on undesexed animals.
The contraceptive type ultimately depends on how frequent the programs are to be run:

One Visit per Year: If only one visit a year is available, then Suprelorin® can be used. One visit still misses any dogs that were born and reached a breeding age, so it is never ideal to have just one visit. Additionally, other contraceptives will not act for a long enough period. Using Suprelorin® can become a very expensive exercise and can often cost more than having another two to three visits each year.
2+ Visits per Year: If two or more visits a year are available, then it is better to go with the drug MPA.  This is a cheaper option and is extremely effective.  Another added advantage is that more regular visits allow more desexings to be performed, and ultimately provide longer lasting population control results in the community’s dogs.

Can anyone give this drug?

Unfortunately no, and generally there are good reasons. These drugs are what's known as prescription drugs and must be either administered or dispensed by a veterinarian. Overdosage can lead to health problems in the animal that may not be reversible. Also these drugs can be dangerous to people, so caution must be used. A skilled veterinary operator is well versed in administering these drugs.

If you would like further information, please contact us on [email protected] or call 08 89723599.
Dr Alexander Burleigh BSc(Vet) BVSc
Dr Alex Burleigh is based in Katherine, NT at Katherine Veterinary Clinic, part of Northern Territory Veterinary Services. He is a part owner and one of the senior veterinarians at both Katherine Veterinary Clinic and Alice Veterinary Centre. Dr Alex Burleigh is a published author with works appearing in veterinary texts, scientific journals and online websites. He consults regularly at both practices.
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